Download CLC Genomics Workbench 10.1.0 Full (cracked)
FEATURES:
CLC Genomics Workbench supports the complete resequencing pipeline for detecting and comparing genetic variants. When dealing with high sample volumes efficient algorithms reduce run time while customizable analysis workflows and batch processing shorten hands-on time to a minimum.
CLC Genomics Workbench allows you to focus on the biological interpretation of detected variants.
Recent improvements promise deeper insights into transcriptional regulation even in the absence of control sample. Transcription factor ChIP-seq exposes defined peak regions characteristic of transcription binding sites throughout the whole genome. All made accessible through our tried and trusted interactive graphical user interface.
Workflows streamline selected tools into one analysis. Workflows can be run in batch making them a powerful tool for processing large numbers of samples with minimal user interventions. You can easily set up your own workflows and create and share workflow installer files with colleagues or other researchers following your scientific publications. Commercial add-ons introduce preconfigured example workflows to get you from data to publication faster.
The free “Advanced RNA-Seq plugin” integrates all the analysis steps – from secondary analysis of the reads to sophisticated statistics – into easy-to-use workflows, and gives access to a wide range of experimental designs, from case-control or multi-group experiments to multi-factorial experiments. All tools account for differences due to sequencing depth, removing the need to normalize input data. Multi-factorial statistics control for batch effects and support paired studies. Statistical results can be visualized in a genomic context as tracks, in a table view, or through the many visualization options leveraging metadata: volcano plots, 2D Heatmaps, Principal Component Analysis and Venn diagrams.
CLC Genomics Workbench offers a range of accurate variant detectors to detect single nucleotide variants (SNVs), multi-nucleotide variants (MNVs), small to medium sized insertions, deletions or replacements, as well as large structural variants. Algorithms for the sensitive detection of so called “low frequency” variants supported only by a small fraction of mapped reads complete the detection tools.To make sense of detected variants CLC Genomics Workbench offers a range of filter and comparison tools.Acetylation of histones is an important epigenetic adaptation associated with chromatin decondensation and up-, or down-regulated gene expression. The Histone ChIP-Seq plugin for CLC Genomics Workbench detects evidence for Histone acetylation marks in genes or other predefined genomic regions.
Cytosine methylation is probably the best-studied form of epigenetic regulation of gene expression. The Bisulfite Sequencing plugin for CLC Genomics Workbench offers an all-in-one solution to common problems that scientists face when studying cytosine methylation data.
DOWNLOAD LINK
Niciun comentariu:
Trimiteți un comentariu